magnesium
Question:
Med Hypotheses 2002 Jan;58(1):47-60 The central role of magnesium deficiency in Tourette’s syndrome: causal relationships between magnesium deficiency, altered biochemical pathways and symptoms relating to Tourette’s syndrome and several reported comorbid conditions. Grimaldi BL. Prior studies have suggested a common etiology involved in Tourette’s syndrome and several comorbid conditions and symptomatology. Reportedly, current medications used in Tourette’s syndrome have intolerable side-effects or are ineffective for many patients. After thoroughly researching the literature, I hypothesize that magnesium deficiency may be the central precipitating event and common pathway for the subsequent biochemical effects on substance P, kynurenine, NMDA receptors, and vitamin B6 that may result in the symptomatology of Tourette’s syndrome and several reported comorbid conditions. These comorbid conditions and symptomatology include allergy, asthma, autism, attention deficit hyperactivity disorder, obsessive compulsive disorder, coprolalia, copropraxia, anxiety, depression, restless leg syndrome, migraine, self-injurious behavior, autoimmunity, rage, bruxism, seizure, heart arrhythmia, heightened sensitivity to sensory stimuli, and an exaggerated startle response. Common possible environmental and genetic factors are discussed, as well as biochemical mechanisms. Clinical studies to determine the medical efficacy for a comprehensive magnesium treatment option for Tourette’s syndrome need to be conducted to make this relatively safe, low side-effect treatment option available to doctors and their patients.
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– Hide quoted text — Show quoted text – >Med Hypotheses 2002 Jan;58(1):47-60 >The central role of magnesium deficiency in Tourette’s syndrome: causal >relationships between magnesium deficiency, altered biochemical pathways and >symptoms relating to Tourette’s syndrome and several reported comorbid >conditions. >Grimaldi BL. >Prior studies have suggested a common etiology involved in Tourette’s >syndrome and several comorbid conditions and symptomatology. Reportedly, >current medications used in Tourette’s syndrome have intolerable >side-effects or are ineffective for many patients. After thoroughly >researching the literature, I hypothesize that magnesium deficiency may be >the central precipitating event and common pathway for the subsequent >biochemical effects on substance P, kynurenine, NMDA receptors, and vitamin >B6 that may result in the symptomatology of Tourette’s syndrome and several >reported comorbid conditions. These comorbid conditions and symptomatology >include allergy, asthma, autism, attention deficit hyperactivity disorder, >obsessive compulsive disorder, coprolalia, copropraxia, anxiety, depression, >restless leg syndrome, migraine, self-injurious behavior, autoimmunity, >rage, bruxism, seizure, heart arrhythmia, heightened sensitivity to sensory >stimuli, and an exaggerated startle response. Common possible environmental >and genetic factors are discussed, as well as biochemical mechanisms. >Clinical studies to determine the medical efficacy for a comprehensive >magnesium treatment option for Tourette’s syndrome need to be conducted to >make this relatively safe, low side-effect treatment option available to >doctors and their patients.
Yep, I find all my vitamins and mineral supplements very helpful and not HARMFUL! And, it does help. Many symptoms have disappeared totally. aSymptoms have lessened markedly on many AyayMy symptoms really helps. My symptoms have lessened markedly since I began taking Vitamin B-100 complex, then Vitamin C and ataddiStill taking my magnesium
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> No Squiggles, I’m not Ray from ASAP, so put the claws away.
hee. pity – i just filed them – next! lol Squiggles p.s. Bruce Springsteen huh? I used to listen to him. — U.S. Constitution: First Amendment Congress shall make no law respecting an establishment of religion, or prohibiting the free exercise thereof; or abridging the freedom of speech, or of the press; or the right of the people peaceably to assemble, and to petition the Government for a redress of grievances.
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Hi Lar, What do you take as a benzo? I can’t remember what you said you take at night…it’s been awhile since I visited this newsgroup. I got a prescr. for Klonopin. I ordered Kava Kava for the day also but haven’t taken this yet. What foods have natural benzo in them? I’ve seen mentioned Green Tea..with L-theanine. Let me throw a link your way. This one is on Klonopin, from cfc page. http://virtualhometown.com/dfwcfids/medical/klonopin.html
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Green tea will give you a caffeine lift, so it certainly wouldn’t work like a "natural" benzo.
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>Hi Lar, >What do you take as a benzo? I can’t remember what you said you take >at night…it’s been awhile since I visited this newsgroup. >I got a prescr. for Klonopin. I ordered Kava Kava for the day also >but haven’t taken this yet. What foods have natural benzo in them? >I’ve seen mentioned Green Tea..with L-theanine. >Let me throw a link your way. This one is on Klonopin, from cfc page. >http://virtualhometown.com/dfwcfids/medical/klonopin.html
Hi ,Rainking How did the tianeptine work out?
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> Hi Lar, > What do you take as a benzo? I can’t remember what you said you take > at night…it’s been awhile since I visited this newsgroup.
Temazepam. > I got a prescr. for Klonopin. I ordered Kava Kava for the day also > but haven’t taken this yet. What foods have natural benzo in them?
Dunno. – Hide quoted text — Show quoted text -> I’ve seen mentioned Green Tea..with L-theanine. > Let me throw a link your way. This one is on Klonopin, from cfc page. > http://virtualhometown.com/dfwcfids/medical/klonopin.html
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> Hi ,Rainking > How did the tianeptine work out?
Stopped it while back. I have some kind of immune system disorder, not depression.
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> Magnesium was expiremented with as an add-on therapy in an ER setting. > Appareltly it was not a success as the practice was dropped.
It’s not exactly been dropped (there is no one person who can ‘drop’ it). Let’s just say that in light of conflicting studies there is probably a subgroup of patients who get benefit and we don’t know exactly what group that is if it indeed exists. In the doses typically used for asthma there is probably no harm in giving it but given that the sorts of people you use this on are already getting multiple other drugs and therapies simultaneously it’s difficult to separate out the effect of the Mg on a given patient without having a large study with good controls. Many of us will try Mg IV in refractory patients and most get better but who knows if it was the Mg that did it or just the accumulation of all the other therapies in progress (and of course for that particular individual who gets better who cares). – Don Elton Columbia, SC http://www.midcarolina.org
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>Magnesium was expiremented with as an add-on therapy in an ER setting.
When my daughter had a severe allergic reaction, one of the things they put in her IV was magnesuim. They told me it was to make the medicine work better. This was in Dec. 1999
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> >Magnesium was expiremented with as an add-on therapy in an ER setting. > When my daughter had a severe allergic reaction, one of the things they put in > her IV was magnesuim. They told me it was to make the medicine work better. > This was in Dec. 1999
I got mine in July of 1999. — Lisa M. DeSavage Hinsbar Laboratories, Inc. www.hinsbarlabs.com
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> Oral calicium and magnesium seem to help muscle cramps for me. Magnesium > also seem good for constipation. I can’t tell it does anything for asthma.
Bronchodilator type medications can interfeer with magnesium absorbtion which can cause cramping.
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Yes! Whenever I have bad asthma attacks they give me Magnesium IV. It seems to work in combination of other meds.
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(LisaKatieT) writes: >Yes! Whenever I have bad asthma attacks they give me Magnesium IV. It seems >to work in combination of other meds.
What other meds… scratching the big toe of your left foot can appear to be a asthma remedy too, if it’s done in combination with prescribed meds. Sheldon On a recent Night Court rerun, Judge Harry Stone had a wonderful line: "I try to keep an open mind, but not so open that my brains fall out."
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My wife has RA with cough-variant asthma and she has received magnesium several times with great success. Typically in combo with solumedrol. – Hide quoted text — Show quoted text – >Yes! Whenever I have bad asthma attacks they give me Magnesium IV. It seems >to work in combination of other meds.
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A Study showing significant reduction of acute asthma after infusion of magnesium http://www.ama-assn.org/special/asthma/library/readroom/magnfull.htm – Hide quoted text — Show quoted text -> I got magnesium via an I.V. in an E.R. once to try to break my asthma > attack. Other than hurting my arm like all get out, it didn’t work. > And no I was not hyperventilating. I wouldn’t try the magnisium route > again. Waste of insurance money and too painful. 
> Magnesium was expiremented with as an add-on therapy in an ER setting. > Appareltly it was not a success as the practice was dropped. > Oral magnesium supplements have been tested and found to be useless for the > treatment of asthma. > Of course the people selling the supplements are going to say that "it is > said by many to help (inset disease here)." They won’t sell very many > supplements if they admit that the stuff is useless. > > Has anyone had any luck with magnesium supplements? I have been taking > it > > for several years now, but with all the other medications I am on I was > not > > aware of any effect. Magnesium is said by many to help alleviate asthma. > Has > > anyone anything on this? > — > Lisa M. DeSavage > Hinsbar Laboratories, Inc. > www.hinsbarlabs.com
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Actually I did read a study that said participants reported improved symptoms, but none of the typical asthma metrics showed improvement. I tried it for a couple of months, didn’t feel any difference though. Eur Respir J 1997 Oct;10(10):2225-2229 Investigation of the effect of short-term change in dietary magnesium intake in asthma. Hill J, Micklewright A, Lewis S, Britton J Division of Respiratory Medicine, City Hospital, Nottingham, UK. Epidemiological evidence suggests that a low dietary intake of magnesium is associated with impaired lung function, bronchial hyperreactivity and wheezing. This study was designed to investigate whether short-term alterations of dietary magnesium intake have an effect on the clinical control of asthma. In a randomized, double-blind, placebo-controlled, cross-over study, 17 asthmatic subjects adhered to a low magnesium diet for two periods of 3 weeks, preceded and separated by a 1 week run-in/wash-out, in which they took either placebo or magnesium (400 mg x day(-1)) tablet supplementation. Forced expiratory volume in one second (FEV1) and the provocative dose of methacholine required to cause a 20% fall in FEV1 from baseline (PD20,FEV1) were measured at the beginning and end of each treatment period, and variation in peak expiratory flow (PEF) rate, bronchodilator use and symptom scores recorded throughout. Asthma symptom scores were significantly lower during the magnesium treatment period, the median (95% confidence interval) difference from placebo being 3.8 (0.5-7.0) symptom points per 7 days (p=0.02). However, there was no significant improvement in FEV1, PD20,FEV1, log amplitude percentage mean PEF variation or bronchodilator use during magnesium supplementation. A high magnesium intake was associated with improvement in symptom scores, though not in objective measures of airflow or airway reactivity, in these stable asthmatic subjects. Publication Types: .Clinical trial .Randomized controlled trial
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Has anyone had any luck with magnesium supplements? I have been taking it for several years now, but with all the other medications I am on I was not aware of any effect. Magnesium is said by many to help alleviate asthma. Has anyone anything on this?
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I am taking 500mg daily for a few weeks now.. Along with other supplements, and have not needed an inhales since the start of the month. – Hide quoted text — Show quoted text -> Has anyone had any luck with magnesium supplements? I have been taking it > for several years now, but with all the other medications I am on I was not > aware of any effect. Magnesium is said by many to help alleviate asthma. Has > anyone anything on this?
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I got magnesium via an I.V. in an E.R. once to try to break my asthma attack. Other than hurting my arm like all get out, it didn’t work. And no I was not hyperventilating. I wouldn’t try the magnisium route again. Waste of insurance money and too painful. > Has anyone had any luck with magnesium supplements? I have been taking it > for several years now, but with all the other medications I am on I was not > aware of any effect. Magnesium is said by many to help alleviate asthma. Has > anyone anything on this?
– Lisa M. DeSavage Hinsbar Laboratories, Inc. www.hinsbarlabs.com
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> I got magnesium via an I.V. in an E.R. once to try to break my asthma > attack. Other than hurting my arm like all get out, it didn’t work. > And no I was not hyperventilating. I wouldn’t try the magnisium route > again. Waste of insurance money and too painful.
Magnesium was expiremented with as an add-on therapy in an ER setting. Appareltly it was not a success as the practice was dropped. Oral magnesium supplements have been tested and found to be useless for the treatment of asthma. Of course the people selling the supplements are going to say that "it is said by many to help (inset disease here)." They won’t sell very many supplements if they admit that the stuff is useless. – Hide quoted text — Show quoted text -> Has anyone had any luck with magnesium supplements? I have been taking it > for several years now, but with all the other medications I am on I was not > aware of any effect. Magnesium is said by many to help alleviate asthma. Has > anyone anything on this? > — > Lisa M. DeSavage > Hinsbar Laboratories, Inc. > www.hinsbarlabs.com
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Oral calicium and magnesium seem to help muscle cramps for me. Magnesium also seem good for constipation. I can’t tell it does anything for asthma. Gordon Stillwater, OK www.couger.com/gcouger – Hide quoted text — Show quoted text -> I got magnesium via an I.V. in an E.R. once to try to break my asthma > attack. Other than hurting my arm like all get out, it didn’t work. > And no I was not hyperventilating. I wouldn’t try the magnisium route > again. Waste of insurance money and too painful. > Magnesium was expiremented with as an add-on therapy in an ER setting. > Appareltly it was not a success as the practice was dropped. > Oral magnesium supplements have been tested and found to be useless for the > treatment of asthma. > Of course the people selling the supplements are going to say that "it is > said by many to help (inset disease here)." They won’t sell very many > supplements if they admit that the stuff is useless. > > Has anyone had any luck with magnesium supplements? I have been taking > it > > for several years now, but with all the other medications I am on I was > not > > aware of any effect. Magnesium is said by many to help alleviate asthma. > Has > > anyone anything on this? > — > Lisa M. DeSavage > Hinsbar Laboratories, Inc. > www.hinsbarlabs.com
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> I recently read a summary from a scientific journal(1995) suggesting > that increased consumption of magnesium is very beneficial for > asthmatics–preventing attacks or lessening their severity. Does anyone > have knowledge or experience with taking magnesium?
I started taking magnesium because I had read something similar. While I can’t say that it has helped my asthma, I can confirm that it has eliminated all of the cramps I used to get from my meds.
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> I recently read a summary from a scientific journal(1995) suggesting > that increased consumption of magnesium is very beneficial for > asthmatics–preventing attacks or lessening their severity. Does anyone > have knowledge or experience with taking magnesium?
I started taking magnesium, about three times the RDA, back in February and have been very pleased with the results. It hasn’t "cured" my asthma (I wish!) but it has enabled me to cut way back on my meds without any increase in attacks. In fact, I’ve only had three this summer (one a month), and they were very minor, knocked down immediately with a couple puffs of Proventil! Usually, if I have what I think of as a minor attack I’m in bad shape for a week or more afterwards, prone to further attacks. And I spent my first spring in years without a course of prednisone, but we had a drought so I can’t be sure if it was the dry weather or the magnesium that kept me off pred. Of course, I haven’t yet gone through ragweed and cedar seasons with magnesium. That will be the real test. I have high hopes that this Christmas I won’t be on prednisone for the holidays. Laura
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I take a magnesium supplement 3 times a day. I have never made the magnesium/good-breathing connection, but I do feel that it has helped immensely with my heart irregularities and overall nerves. Peace, Don >I recently read a summary from a scientific journal(1995) suggesting >that increased consumption of magnesium is very beneficial for >asthmatics–preventing attacks or lessening their severity. Does anyo >ne >have knowledge or experience with taking magnesium?
– NETWATCH a division of ROCKOUT
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– Hide quoted text — Show quoted text -> I recently read a summary from a scientific journal(1995) suggesting > that increased consumption of magnesium is very beneficial for > asthmatics–preventing attacks or lessening their severity. Does anyone > have knowledge or experience with taking magnesium? > I started taking magnesium, about three times the RDA, back in February > and have been very pleased with the results. It hasn’t "cured" my asthma > (I wish!) but it has enabled me to cut way back on my meds without any > increase in attacks. In fact, I’ve only had three this summer (one a > month), and they were very minor, knocked down immediately with a > couple puffs of Proventil! Usually, if I have what I think of as a minor > attack I’m in bad shape for a week or more afterwards, prone to further > attacks. And I spent my first spring in years without a course of > prednisone, but we had a drought so I can’t be sure if it was the dry > weather or the magnesium that kept me off pred. > Of course, I haven’t yet gone through ragweed and cedar seasons with > magnesium. That will be the real test. I have high hopes that this > Christmas I won’t be on prednisone for the holidays. > Laura
I find that Magnesium helps. However, I take a multivitamin in the am and a supplemental Magnesium in the pm. I tried the Magnesium plus Calcium supplements, and it seemed to make things worse. (Tried it since lack of calcium can also cause muscle cramping, or so I was advised.) A multivitamin is a good place to start; but I remember reading that you don’t actually absorb all of what’s in it. Much of the vitamin C, for instance, and B vitamins too, go right through. A small dose twice a day probably gets more into your system. Just don’t go for megadoses. asterisk
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I recently read a summary from a scientific journal(1995) suggesting that increased consumption of magnesium is very beneficial for asthmatics–preventing attacks or lessening their severity. Does anyone have knowledge or experience with taking magnesium?
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>I recently read a summary from a scientific journal (1995) suggesting >that increased consumption of magnesium is very beneficial for >asthmatics–preventing attacks or lessening their severity. Does anyone >have knowledge or experience with taking magnesium?
I sent Ann the file of anecdotes on this that I’ve collected along the way, much from this group. Here’s something I found on my bookshelf. Certainly not a new discovery! From Wise Encyclopedia of Cookery, 1971: "Healthy lungs show twice as much magnesium as lime [i.e. calcium carbonate]. Magnesium is a cell-builder, particularly of the nervous system and lung tissues. Magnesium salts assist in reducing foreign matter and waste, and in carrying them out of the system, thus invigorating the excretory organs and producing pressure, without which metabolism would be impossible." I highly recommend taking magnesium. It is in hard water, coffee, and dark green vegetables. Also taking magnesium before going to bed helps some people sleep better, i.e. more soundly. The anecdotes also mention taking B6. Don.
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> I recently read a summary from a scientific journal(1995) suggesting > that increased consumption of magnesium is very beneficial for > asthmatics–preventing attacks or lessening their severity. Does anyone > have knowledge or experience with taking magnesium?
Sample of one experience: I took magnisium supplements for a while, and my asthma seemed to get better for a while, then stayed the same. I stopped taking it, and noticed no change…I asked my doctor, who suggested (to ME, YOUR SITAUATION MAY VARY) taking smallish dosages couldn’t hurt and might help. Thus it doesn’t seem to be a miracle cure, but it’s worth writing down to ask your doctor about the next time you see her/him. Scott-T.
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