Ipratropium bromide with or without albuterol?
Salmeterol Fluticasone is a medication used to treat asthma spasms. Buy salmeterol inhaler and feel better today!
Question:
- Hide quoted text — Show quoted text – >Does anybody know about or have experience with Zenith brand albuterol? I >think >that might be a generic brand. Ventolin seemed to work better for me, but the >comparison is dubious because with the Zenith brand, I might have reached a >stage where albuterol would have less effect. Also, my last use of Zenith >brand >seems to have contributed to an upset stomach without being the entire cause, >however now if I still had any albuterol, I would be very reluctant to use it >on a nonempty stomach unless the breathing situation were really dire. >To Glenn Gilbreath: I remember you from Arachne list, dating to when >Freewwweb >offered free Internet service, and the user could use their own software, and >subsequently Freewwweb was taken over by Juno. I will send an email.
Thomas, Yes, good old FreeWWWeb! I gave up on the free ISP stuff totally… and found a national alternative that lets ME, the owner/user of the computer, decide with what and how I will access the Internet and WWW…hehe…I still see you on the Arachne list! RE: Zenith Brand…yes, it’s just a generic label. If it is the cause of your upset stomach or not working as well, that is sort of difficult to say. Generally speaking, Zenith has a decent reputation in pharmaceutical circles. I’ve dispensed their label products and never had any problems…even used them myself. There was a severe shortage of albuterol last year though…so it could be possible a faulty batch made it into circulation. Ipratropium by itself will usually not be as effective as desired, though it is quite good at preventing acute asthma attack, and can lessen severity of an attack. Albuterol, as well as other sympathetic amides (there, Alan, that better?, hehe <{;-) ) such as Maxair, Isuprel Metaprel etc. dilate the bronchial tubes by direct action on the smooth muscle controlling diameter of the bronchi. But, this action, by sort of mimicing adrenaline, can also lead to the "jitters" as many of my patients describe them. The combination of Ipratropium and especially albuterol has proven to be highly effective. Recently, say the last 2 years or so, ipratropium has been combined with the 12 hour beta-agonist Salmeterol (Serevent), and is also being quite well received (Advair Diskus)…the precaution I give to someone that has been using say Combivent, is that Advair is ONLY to be used NO MORE THAN TWICE A DAY. This is due to the salmeterol… C U L8R! Wiz <{;-) Wizard57M Glenn Gilbreath Jr. Registered Pharmacist — DOS Internet, Close Windows and Keep the Internet Open! —
Response:
> Thomas, > Yes, good old FreeWWWeb! I gave up on the free ISP stuff totally…
and found a national alternative that lets ME, the owner/user of the computer, decide with what and how I will access the Internet and WWW…hehe…I still see you on the Arachne list! > RE: Zenith Brand…yes, it’s just a generic label. If it is the
cause of your upset stomach or not working as well, that is sort of difficult to say. Generally speaking, Zenith has a decent reputation in pharmaceutical circles. I’ve dispensed their label products and never had any problems…even used them myself. There was a severe shortage of albuterol last year though…so it could be possible a faulty batch made it into circulation. > Ipratropium by itself will usually not be as effective as desired,
though it is quite good at preventing acute asthma attack, and can lessen severity of an attack. Albuterol, as well as other sympathetic amides (there, Alan, that better?, hehe <{;-) ) such as Maxair, Isuprel Metaprel etc. dilate the bronchial tubes by direct action on the smooth muscle controlling diameter of the bronchi. But, this action, by sort of mimicing adrenaline, can also lead to the "jitters" as many of my patients describe them. The combination of Ipratropium and especially albuterol has proven to be highly effective. Recently, say the last 2 years or so, ipratropium has been combined with the 12 hour beta-agonist Salmeterol (Serevent), and is also being quite well received (Advair Diskus)…the precaution I give to someone that has been using say Combivent, is that Advair is ONLY to be used NO MORE THAN TWICE A DAY. This is due to the salmeterol… > C U L8R!
Wiz <{;-) Wizard57M Glenn Gilbreath Jr. Registered Pharmacist Free ISPs seem to have diminished, and I gave up on them too. Is Zenith brand albuterol any business relation to Zenith electronics? I think Zenith (electronics) has been known for radios since long before albuterol existed. Glenn, I think you erred on what Advair Diskus contains. I received the direct-mail ad for Advair Diskus with a card for free Ventolin (albuterol) inhaler that can be used up to four times. According to the product information, the active ingredients are fluticasone propionate (corticosteroid) and salmeterol xinafoate. Recommended dosage is twice a day. They say to keep in a dry place between 20 and 25 C (it’s 28 C here now indoors which is cool for this time of year and well within my comfort range). Diskus contains 60 doses (blisters), and they say to discard one month after opening the device or when all blisters have been used, whichever comes first. So the patient is really supposed to use the Diskus consistently lest it expire. Taking a month to be 31 days even if it’s February, what happens on day 32? I guess I’d need the ipratropium bromide because of the mucus and the dreaded throat tickle, rather than albuterol alone.
Response:
> I use Combivent. it is albuterol plus the ipratropium bromide. > Supposedly it helps in the reduction of mucus produced…or so I was told by > the doc.
I’ve heard of Combivent through alt.support.asthma, but that was long after April 1997. Does anybody know when Combivent first became available? Relating to DTC from another thread, I get ads and coupons in the mail for various meds like Serevent Diskus (salmeterol xinafoate) inhaler endorsed by Olympic athlete Jackie Joyner-Kersey, and more recently Advair Diskus inhaler (salmeterol + fluticasone propionate) with free Ventolin (albuterol) inhaler for each of the first four purchases of Advair Diskus. I would have to get prescriptions for both. Glaxo Smith Kline is trying to hook me for big money! No freebies such as Jackie Joyner-Kersey might get for the endorsement. Albuterol for me feels like a semi-rescue inhaler, I’d need ipratropium bromide to better qualify as a rescue inhaler.
Response:
>>> Mastcell-stabilisers include cromoglicate, azelastine, oxatomide, > ketotifen, >> nedocromil and lodoxamide. > And, didn’t you leave out cromolyn sodium??? That ones been around > for ages…. > No, it’s called cromoglicate in this part of the world 
> MB
Might it be cromoglycate? Lp
Response:
> Might it be cromoglycate?
Yes it might… I had to make up a translation from the Dutch "cromoglicinezuur" (zuur = acid) or "natriumcromoglicaat" (natrium = sodium) mto something that looked like it could be English MB
Response:
Does anybody know about or have experience with Zenith brand albuterol? I think that might be a generic brand. Ventolin seemed to work better for me, but the comparison is dubious because with the Zenith brand, I might have reached a stage where albuterol would have less effect. Also, my last use of Zenith brand seems to have contributed to an upset stomach without being the entire cause, however now if I still had any albuterol, I would be very reluctant to use it on a nonempty stomach unless the breathing situation were really dire. To Glenn Gilbreath: I remember you from Arachne list, dating to when Freewwweb offered free Internet service, and the user could use their own software, and subsequently Freewwweb was taken over by Juno. I will send an email.
Response:
> >Mastcell-stabilisers include cromoglicate, azelastine, oxatomide, ketotifen, >nedocromil and lodoxamide. > And, didn’t you leave out cromolyn sodium??? That ones been around > for ages….
No, it’s called cromoglicate in this part of the world MB
Response:
> Hey Guys…I was trying to be brief, the folks I was conversing with > are not pharmacist, nor Pharm D, nor PhD…I figured it would be best > at this time to just explain what it does…
Do you think saying "Ipratrpium is termed a "mast cell stabilizer", meaning it stabilizes cell membranes of the cells lining the bronchial tubes that release histamine in response to asthma triggering agents." is much more comprehensible for a laymen than saying it is anti-cholinergic? This is not a personal attack, I step in this pittfall myself as well, when I think I explain something in simple terms to a laymen it turns out I have to much "professional deformation" and still speak in my jargon sometimes. > yes, it is anti-cholinergic, > anti-muscarinic…thereby stabilizing the mast cells,
Mast cells have muscarin-receptors and secrete histamine after stimulation by acetylcholine? I am not saying this isn’t true, but it’s the first time I have heard this. AFAIK the action of ipratropium is dilation of the bronchii by effect on smooth muscle-tissue and inhibition of mucus-secretion by effect on mucus-glands. (Apologies for my English, I am not a native speaker.) MB
Response:
>> Ipratrpium is termed a "mast cell > stabilizer", meaning it stabilizes cell membranes of the cells lining the > bronchial tubes that release histamine in response to asthma triggering > agents. >To the best of my knowledge, ipratropium is a muscarin-antagonist, so a >parasympaticolytic substance. >Mastcell-stabilisers include cromoglicate, azelastine, oxatomide, ketotifen, >nedocromil and lodoxamide. >MB
And, didn’t you leave out cromolyn sodium??? That ones been around for ages…. Wiz Wizard57M Glenn Gilbreath Jr. Registered Pharmacist — DOS Internet, Close Windows and Keep the Internet Open! —
Response:
> Ipratrpium is termed a "mast cell > stabilizer", meaning it stabilizes cell membranes of the cells lining the > bronchial tubes that release histamine in response to asthma triggering > agents.
To the best of my knowledge, ipratropium is a muscarin-antagonist, so a parasympaticolytic substance. Mastcell-stabilisers include cromoglicate, azelastine, oxatomide, ketotifen, nedocromil and lodoxamide. MB
Response:
>> Ipratrpium is termed a "mast cell > stabilizer", meaning it stabilizes cell membranes of the cells lining the > bronchial tubes that release histamine in response to asthma triggering > agents. >To the best of my knowledge, ipratropium is a muscarin-antagonist, so a >parasympaticolytic substance. >Mastcell-stabilisers include cromoglicate, azelastine, oxatomide, ketotifen, >nedocromil and lodoxamide. >MB
Hey Guys…I was trying to be brief, the folks I was conversing with are not pharmacist, nor Pharm D, nor PhD…I figured it would be best at this time to just explain what it does…yes, it is anti-cholinergic, anti-muscarinic…thereby stabilizing the mast cells, preventing the release of histamine which acts as a broncho-constrictor…when you are talking with "non-scientifically oriented" patients, you DON’T want to give them an explanation 1000 feet over their heads… C U L8R! Wiz <{;-) (a REAL LIFE, honest-to-goodness, practicing pharmacist… don’t live in ivory towers….) Wizard57M Glenn Gilbreath Jr. Registered Pharmacist — DOS Internet, Close Windows and Keep the Internet Open! —
Response:
gee what made me think that ipratropium was an anticholinergic, that decreased secretions, but also caused some bronchial relaxation.
Response:
> gee what made me think that ipratropium was an anticholinergic, that > decreased secretions, but also caused some bronchial relaxation.
You know, I thought so too, and the PDR thinks the same as we. Larry
Response:
Thanks. I suspected it had something of the like. I usually look up every new med to be certain what I am being given……’cause I like to know. – Hide quoted text — Show quoted text -> What is the effect of ipratropium bromide inhaler on an asthma > attack without albuterol (the latter aka salbutamol)? I am assuming > a situation where the sufferer can wait 15 minutes or more for > relief. > I got albuterol and ipratropium bromide inhalers April 8, 1997 on > prescription. > Instructions were to take two puffs of the albuterol one minute > apart followed ten minutes later by two puffs of the ipratropium > bromide one minute apart. Albuterol was only partially effective, > left me feeling sort of in a twilight zone until I got the > ipratropium bromide. I don’t know if the relief was due to > just the ipratropium bromide or whether there is a synergy between > the two inhalers. Now is too late to try with these inhalers, since > I don’t have the inhalers any more: they were long past expiration > and pretty useless from what I was advised. Nevertheless the > question still bugs me, and I could possibly get a new prescription. > Hiya Thomas! > Don’t I know yo from another email group, hehe? Like maybe SurvPC or > Arachne? Anyway, albuterol is what we term "rescue inhaler", it is > used to dilate the bronchial tubes, is usually effective within 15 to > 30 minutes and lasts normally from 4 to 6 hours. Ipratrpium is > termed a "mast cell stabilizer", meaning it stabilizes cell membranes > of the cells lining the bronchial tubes that release histamine in > response to asthma triggering agents. This way, it is more for > prevention only, it doesn’t help much if you are suffering an acute > attack. Recently, many asthma patients have been prescribed Serevent > Inhaler (salmeterol), which is a long lasting anti-adrenergic agent, > working in similar fashion to albuterol, but for 12 hour duration, is > dosed at 2 puffs, no more than twice a day. But, you should still > have a "rescue" inhaler such as albuterol (Proventil, Ventolin) on > hand for acute flare up. If you would like further information, zap > an email to my email address, I think I gave it to you on > C U L8R! > Wiz <{;-) > Wizard57M > Glenn Gilbreath Jr. > Registered Pharmacist > — DOS Internet, Close Windows and Keep the Internet Open! —
– Cry havoc! and let loose the dogs of war….. — William Shakespeare
Response:
- Hide quoted text — Show quoted text – > I use Combivent. it is albuterol plus the ipratropium bromide. >Supposedly it helps in the reduction of mucus produced…or so I was told by >the doc. > What is the effect of ipratropium bromide inhaler on an asthma attack > without albuterol (the latter aka salbutamol)? I am assuming a > situation where the sufferer can wait 15 minutes or more for relief. > I got albuterol and ipratropium bromide inhalers April 8, 1997 on > prescription. Instructions were to take two puffs of the albuterol > one minute apart followed ten minutes later by two puffs of the > ipratropium bromide one minute apart. Albuterol was only partially > effective, left me feeling sort of in a twilight zone until I got the > ipratropium bromide. I don’t know if the relief was due to just the > ipratropium bromide or whether there is a synergy between the two > inhalers. Now is too late to try with these inhalers, since I don’t > have the inhalers any more: they were long past expiration and pretty > useless from what I was advised. Nevertheless the question still > bugs me, and I could possibly get a new prescription. >– >Cry havoc! and let loose the dogs of war….. — William Shakespeare
John, Read my reply to Thomas…and yes, Combivent helps to decrease mucous secretions, by blocking the histamine release via mast cell stimulation. Same invitation regarding email is extended to you… C U L8R! Wiz <{;-) Wizard57M Glenn Gilbreath Jr. Registered Pharmacist — DOS Internet, Close Windows and Keep the Internet Open! —
Response:
- Hide quoted text — Show quoted text – >What is the effect of ipratropium bromide inhaler on an asthma attack without >albuterol (the latter aka salbutamol)? I am assuming a situation where the >sufferer can wait 15 minutes or more for relief. >I got albuterol and ipratropium bromide inhalers April 8, 1997 on >prescription. >Instructions were to take two puffs of the albuterol one minute apart followed >ten minutes later by two puffs of the ipratropium bromide one minute apart. >Albuterol was only partially effective, left me feeling sort of in a twilight >zone until I got the ipratropium bromide. I don’t know if the relief was due >to >just the ipratropium bromide or whether there is a synergy between the two >inhalers. Now is too late to try with these inhalers, since I don’t have the >inhalers any more: they were long past expiration and pretty useless from what >I was advised. Nevertheless the question still bugs me, and I could possibly >get a new prescription.
Hiya Thomas! Don’t I know yo from another email group, hehe? Like maybe SurvPC or Arachne? Anyway, albuterol is what we term "rescue inhaler", it is used to dilate the bronchial tubes, is usually effective within 15 to 30 minutes and lasts normally from 4 to 6 hours. Ipratrpium is termed a "mast cell stabilizer", meaning it stabilizes cell membranes of the cells lining the bronchial tubes that release histamine in response to asthma triggering agents. This way, it is more for prevention only, it doesn’t help much if you are suffering an acute attack. Recently, many asthma patients have been prescribed Serevent Inhaler (salmeterol), which is a long lasting anti-adrenergic agent, working in similar fashion to albuterol, but for 12 hour duration, is dosed at 2 puffs, no more than twice a day. But, you should still have a "rescue" inhaler such as albuterol (Proventil, Ventolin) on hand for acute flare up. If you would like further information, zap an email to my email address, I think I gave it to you on Arachne…if not, try one of these… C U L8R! Wiz <{;-) Wizard57M Glenn Gilbreath Jr. Registered Pharmacist — DOS Internet, Close Windows and Keep the Internet Open! —
Response:
What is the effect of ipratropium bromide inhaler on an asthma attack without albuterol (the latter aka salbutamol)? I am assuming a situation where the sufferer can wait 15 minutes or more for relief. I got albuterol and ipratropium bromide inhalers April 8, 1997 on prescription. Instructions were to take two puffs of the albuterol one minute apart followed ten minutes later by two puffs of the ipratropium bromide one minute apart. Albuterol was only partially effective, left me feeling sort of in a twilight zone until I got the ipratropium bromide. I don’t know if the relief was due to just the ipratropium bromide or whether there is a synergy between the two inhalers. Now is too late to try with these inhalers, since I don’t have the inhalers any more: they were long past expiration and pretty useless from what I was advised. Nevertheless the question still bugs me, and I could possibly get a new prescription.
Response:
I use Combivent. it is albuterol plus the ipratropium bromide. Supposedly it helps in the reduction of mucus produced…or so I was told by the doc. – Hide quoted text — Show quoted text – > What is the effect of ipratropium bromide inhaler on an asthma attack > without albuterol (the latter aka salbutamol)? I am assuming a > situation where the sufferer can wait 15 minutes or more for relief. > I got albuterol and ipratropium bromide inhalers April 8, 1997 on > prescription. Instructions were to take two puffs of the albuterol > one minute apart followed ten minutes later by two puffs of the > ipratropium bromide one minute apart. Albuterol was only partially > effective, left me feeling sort of in a twilight zone until I got the > ipratropium bromide. I don’t know if the relief was due to just the > ipratropium bromide or whether there is a synergy between the two > inhalers. Now is too late to try with these inhalers, since I don’t > have the inhalers any more: they were long past expiration and pretty > useless from what I was advised. Nevertheless the question still > bugs me, and I could possibly get a new prescription.
– Cry havoc! and let loose the dogs of war….. — William Shakespeare
Response:
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